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The Dirty Dozen and The Clean 15 - Making Organic Easy

The Dirty Dozen and The Clean 15 - Making Organic Easy

Organic isn’t always essential, yet pesticides aren’t something to ignore either. Different fruits and vegetables absorb and hold onto residues in very different ways, and that can influence long-term exposure.

The Dirty Dozen and Clean Fifteen help you focus your organic choices where they make the biggest impact, while keeping everything else simple. Before diving into the lists, here’s a quick look at how pesticides behave and why certain foods truly matter.

 

Why Pesticides Matter: The Science

Pesticides are widely used in conventional farming to protect crops from pests, fungi, and weeds. Although there are safety rules to keep residues low, research shows that repeated exposure to certain types of pesticides - like organophosphates, neonicotinoids, and endocrine-disrupting chemicals - may affect our long-term health.

Some key health concerns include:

  • Hormone disruption: Some pesticides can interfere with hormone signalling
  • Brain and nerve effects: Organophosphate, in particular, has been linked with changes in brain and nervous system development.
  • Gut microbiome imbalance: New studies suggest pesticides could influence the balance of beneficial gut microbes.
  • Cumulative exposure: Even if each food contains only small amounts, eating many foods with residues can add up over time.

This is why it can be helpful to choose organic versions of foods most likely to carry higher pesticide residues.

 

The Dirty Dozen

These fruits and vegetables tend to show the highest pesticide levels in annual testing. Choosing organic versions of these can significantly reduce your intake.

Why These Foods Rank High

These crops often:

  • Are thin-skinned, making them more absorbent.
  • Are prone to pests, so they receive more chemical treatments. · Are sprayed multiple times throughout the season.
  • Hold onto residues even after washing. For example, berries and leafy greens often contain residues from several different pesticides at once. In some studies, more than 30 different types have been found on a single sample. (1,2)

 

The Dirty Dozen (2025)

 

The Clean Fifteen

These foods consistently test low for pesticides and are typically fine to buy conventional. Why These Foods Test Clean These items often:

  • Have thick skins or protective peels. 
  • Require fewer pesticides due to lower pest pressure. 
  • Absorb less of what is sprayed on them. 
  • Are grown in conditions that reduce the need for chemicals. (1,2) 

 

The Clean 15 2025

 

How Pesticides May Affect Health

Hormone Disruption

Some pesticides act like hormone imitators. Even low-level exposure over time may influence reproductive health or thyroid function. Systematic reviews have also linked exposure to endocrine-disrupting pesticides (like certain organophosphates and pyrethroids) with metabolic changes, including obesity. (3)

 

Neurological Effects 

Organophosphates were originally derived from nerve agents. Despite regulation efforts, residues still appear in conventional produce. Chronic low-level exposure has been associated with changes in brain development, especially in children. (4)

 

Immune & Gut Health

  • Emerging studies suggest that pesticide residues can affect the gut‑microbiota–blood‑brain barrier axis. (5)
  • In humans, eating foods containing organophosphates has been linked to changes in beneficial gut microbes. (6)
  • Animal studies also show that pesticide exposure during pregnancy (for example, with chlorpyrifos) can lead to gut imbalance and may weaken the blood–brain barrier in offspring. (7)

 

The “Cocktail Effects”

Even if each pesticide is present in “safe” amounts, constant exposure to multiple residues (sometimes called the “cocktail effect”) may still have an impact. (8)

Studies also link long-term exposure, whether through food or the environment, with an increased risk of chronic conditions, including neurological diseases and certain cancers. (9)

 

When Organic Matters Most

  • Here’s when choosing organic is more impactful:
  • Foods consumed daily (e.g., apples, berries).
  • Children’s diets, since children are more vulnerable.
  • Eating leafy greens and thin‑skinned fruits.
  • During preconception and pregnancy.
  • Supporting gut health, especially if someone already has gut issues.

 

When It Doesn’t Matter As Much

Buying non-organic is usually makes sense when:

  • The food is part of the Clean Fifteen.
  • You plan to peel it (e.g., avocado, mango).
  • The food naturally absorbs little pesticide.
  • You are prioritising the budget.

Remember: Eating a wide variety of fruits and vegetables is always more important than eating organic perfectly.

 

How to Reduce Pesticide Exposure (Practical Tips)

1. Wash Thoroughly

  • Use: Water + friction (most effective)
  • Baking soda soak (best for removing surface pesticides)
  • Avoid commercial produce washes, they’re no more effective than water.

2. Peel When Appropriate: This helps with foods like cucumbers, apples, and carrots.

3. Buy Organic for the Dirty Dozen: A targeted approach prevents unnecessary cost.

4. Support Local & Seasonal: Local growers often use fewer chemicals, even if they’re not certified organic.

5. Diversify Your Diet: Rotating fruits and vegetables reduce repeat exposure to the same pesticide compounds. (10)

 

Final Thoughts

Pesticides are unavoidable in modern farming, but exposure can be minimised. Using a balanced approach; choosing organic for the Dirty Dozen, buying conventional for the Clean Fifteen, and using simple washing techniques allows you to protect your health while staying realistic and budget‑conscious.

 

 

The Gutology Podcast

Watch this clip from our latest episode, where Katie, MD of Microbz, discusses soil health and how pesticides and herbicides affects the food we eat.

 

 

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References

1. Environmental Working Group. (2025). EWG’s 2025 Shopper’s Guide to Pesticides in Produce™ – Methodology [online]. Available at: https://www.ewg.org/foodnews/summary.php#methodology

2. Environmental Working Group. (2025). EWG’s 2025 Shopper’s Guide to Pesticides in Produce™ – Full List. [online] Available at: https://www.ewg.org/foodnews/full-list.php

3. Pérez-Bermejo et al. (2024) Impact of Endocrine Disrupting Pesticide Use on Obesity: A Systematic Review. Biomedicines 12, 2677.

4. Gama J, Neves B, Pereira A. (2022) Chronic Effects of Dietary Pesticides on the Gut Microbiome and Neurodevelopment. Front Microbiol. 13:931440.

5. Abou et al. (2023) Impact of Pesticide Residues on the Gut-Microbiota–Blood–Brain Barrier Axis: A Narrative Review. Int. J. Mol. Sci. 24, 6147.

6. Ueyama et al. (2022) Effects of Pesticide Intake on Gut Microbiota and Metabolites in Healthy Adults. Int J Environ Res Public Health. 20(1):213. 

7. Abou et al. (2024) Maternal exposure to pesticides induces perturbations in the gut microbiota and blood–brain barrier of dams and the progeny, prevented by a prebiotic. Environ Sci Pollut Res 31, 58957–58972.

8. Cao et al. (2024) Pesticide residues: Bringing the gap between environmental exposure and chronic disease through omics. Endotoxicology and Environmental Safety. 287(15):117335.

9. Shekhar et al. (2024) A systematic review of pesticide exposure, associated risks, and long-term human health impacts. Toxicology Reports. 13:101840.

10. Zhou et al. (2025) A comprehensive review on environmental and human health impacts of chemical pesticide usage. Emerging Contaminants. 11(1):100410.