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Hydroxyapatite

Microbiome Friendly

Fluoride Free

"Hydroxyapatite has been studied in lab and clinical settings for its role in enamel remineralisation. That’s why I often suggest sticking with it for at least 3 months to build a consistent routine."

Dr Seb Lomas - Biological Dentist

Vegan Trending

Gutology Hydroxyapatite Toothpaste 120ml

£16.00

A fluoride-free toothpaste formulated with biomimetic hydroxyapatite a mineral that mirrors what’s naturally found in your teeth. It delivers a fresh, clean feel without harsh additives to support your natural microbiome

Gutology Toothpaste is fluoride-free, microbiome-friendly and made with natural ingredients without the synthetic surfactants or preservatives found in many mainstream formulas. Formulated with clinically studied ingredients that support the oral ecosystem.

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Hydroxyapatite is backed by clinical and laboratory research showing how it can bind to enamel surfaces and support remineralisation. Some studies have observed visible improvements after 8 weeks of consistent use especially in early enamel wear.

In laboratory studies, biomimetic hydroxyapatite has been shown to fill exposed dentin tubules (the microscopic channels in enamel that are associated with sensitivity) helping to form a protective mineral layer.

Yes, best for ages 3+ as the mint taste could be strong for little ones.

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Dr Seb Lomas - Biological Dentist

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Yes, best for ages 3+ as the mint taste could be strong for little ones.

Remineralising

Anti-Plaque

Anti-Sensitivity

Biome Friendly

Antimicrobial

Remineralising

Anti-Plaque

Anti-Sensitivity

Why replace your current toothpaste?

You swallow a whole tube of toothpaste every year. Is yours safe to swallow?

Microbiome-friendly

Supports a natural oral microbiome with ingredients you can use everyday.
Helps Rebuild Enamel Surface

Formulated with natural hydroxyapatite a biomimetic mineral shown in lab studies to restore enamel-like surfaces by replenishing calcium and phosphate.
No fluoride. No compromise.

Powered by clinically studied ingredients designed to support enamel strength and oral microbiome balance, without unnecessary additives.
No Harsh Ingredients

Free from SLS and aggressive surfactants. Formulated to support your oral microbiome - never disrupt it.
Fresh breath starts with balance

Your oral microbiome plays a key role in how your breath smells. Supporting that ecosystem helps you feel fresher, without masking.
The Oral-Gut Connection

Your mouth is the gateway to your microbiome. Brushing isn’t just cosmetic it’s a daily ritual that supports the balance your body depends on.

What’s in our toothpaste (and what isn’t)

Many are rethinking traditional formulas not just because of fluoride, but due to ingredients like SLS, parabens, and foaming agents.

Gutology Mineral Toothpaste is formulated without these, using clinically considered alternatives that support the oral microbiome, without disrupting it.

Microbiome-Focused Oral Care

Your mouth is home to a thriving ecosystem of bacteria your oral microbiome.

Gutology Toothpaste is powered by TrueBiotic®, a postbiotic derived from Lactobacillus plantarum HEAL19 and studied for its role in supporting microbial balance.

In lab studies, TrueBiotic® has been shown to:
• Help reduce IL-1β (an inflammation marker) in immune cell models
• Support beneficial bacteria in oral microbiome simulations
• Encourage microbial diversity in preclinical settings

Our fluoride-free formula is designed to work in harmony with your mouth’s natural ecology for a fresher, more balanced start to your day.

The Power of Hydroxyapatite

Hydroxyapatite is a biocompatible mineral that closely reflects the natural structure of enamel.

It helps support a more balanced, mineral-rich surface environment without disrupting the oral microbiome.

Sometimes, science feels a little like magic.

This is more than just cleaning

Gutology Mineral Toothpaste cleans your teeth effectively with a microbiome-friendly formulation.

Gut-Friendly

Protect your microbiome.
Cancel Anytime

No contracts, cancel anytime.
Free Shipping

Free shipping with your monthly order.
Sustain

Long-term oral protection.

Hydroxyapatite

Microbiome Friendly

Fluoride Free

Dr Seb Lomas - Biological Dentist

Vegan Trending

Gutology Hydroxyapatite Toothpaste 120ml

£16.00

The fluoride-free toothpaste formulated with biomimetic hydroxyapatite a mineral that mirrors what’s naturally found in your teeth. It delivers a fresh, clean feel without harsh additives to support your natural microbiome

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Yes, best for ages 3+ as the mint taste could be strong for little ones.

Buy Once

Subscribe & Save

Cancel Anytime
Adjust Delivery Frequency
Free Shipping

Delivery every 3 months

Delivery every 6 months

Delivery every 1 month

Dr Seb Lomas - Biological Dentist

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Yes, best for ages 3+ as the mint taste could be strong for little ones.

Ingredients

GLYCERIN
AQUA
HYDRATED SILICA
HYDROXYAPATITE
GLYCOLIPIDS
XYLITOLNatural sweetener
LACTOBACILLUS FERMENTDerived from Lactobacillus Plantarum HEAL19
CELLULOSE GUM
CALCIUM CARBONATE
MENTHA ARVENSIS LEAF OIL
STEVIOSIDE
MENTHOL
ACACIA SENEGAL GUM
AROMA
MENTHA PIPERITA OIL
EUCALYPTUS OIL
LIMONENE

Directions

Simply use Gutology Toothpaste like your normal toothpaste, twice daily.

Frequently Asked Questions

Have concerns? That’s okay. You can find all your urgent answers right here.

Is this toothpaste worth the price?

Absolutely and here’s why:

At 120ml, Gutology’s toothpaste is significantly bigger than many leading natural alternatives, which often come in 75ml tubes. That means more value per use.

We use biomimetic hydroxyapatite a fluoride-free mineral that mirrors the natural structure of enamel and is studied for its role in supporting surface mineral balance.

Stick with it and save. Our subscription model rewards consistency with better pricing no commitment, cancel anytime.

Is this toothpaste suitable for children?

Yes! Gutology toothpaste is 100% safe for children, thanks to its gentle, fluoride-free formulation. Instead of fluoride, we use biomimetic hydroxyapatite — a clinically proven mineral that helps rebuild and protect tooth enamel, without any risk if swallowed.

It’s also free from harsh foaming agents (like SLS), artificial sweeteners, and synthetic preservatives, making it ideal for growing smiles and sensitive mouths.

For little ones, we also offer a naturally flavoured strawberry version — making brushing time a whole lot easier (and tastier).

Do you test for heavy metals?

Your health is our priority. Every batch is independently tested for heavy metals usingICP-MS (Inductively Coupled Plasma Mass Spectrometry)— one of the most advanced and sensitive detection methods available.
We test for critical elements includinglead, arsenic, mercury, and cadmium, all of which are consistentlybelow detectable limits.
We also screen for other trace elements such asnickel, chromium, cobalt, and zinc— and confirm that all results fallwell within the EU and UK’s strict safety thresholds for daily exposure.
These results are reviewed by our quality team to ensure the highest standards of purity and safety.

Is this product vegan and cruelty-free?

Yes, this has been requested by many nutritionists that we work with. We've achieved this by using a vegetable sourced glycerine in our formulation. It is also 100% cruelty-free.

What if I need more help?

We understand that digestive issues can be complex, that's why we offer a £75 voucher towards advanced microbiome testing to every DigestBox customer.

Allergies

You are responsible for carefully reading any ingredients listed on our website and/or on any packaging, labels and/or leaflets to avoid the risk of allergic or other adverse reactions.

For more information on allergies: click here.

Best

Amazing toothpaste , the taste the texture and it feels fresh .. no going back to heavy duty toothpaste for me 😁

Gutology toothpast

I haven't used it for very long so I think it's too soon to notice any changes. I do however think it's nice to use and not too minty that it burns my mouth, and I like the fact it is fluoride free. I continue to use it.

Very impressed

I’m loving this product, it tastes great, lasts a long time and is a fantastic alternative to regular paste. I’m definitely converted

Im impressed!

I was a bit sceptical at first as I’ve tried numerous toothpaste before but I’m impressed. The toothpaste taste nice makes your mouth feel fresh but it really has whitened my teeth !!!

Reassuring

I’m delighted to have found a toothpaste and mouth rinse that is micro biome friendly. It tastes great and long lasting and needs only a small amount.

Gutology toothpaste

I love this toothpaste it has really helped to heal my mouth and keep a good bacterial flora
Can’t switch back to fluoride now!

Repeat order

Used this toothpaste for a number of years now . Wouldn’t use anything else now

Great flavour!

Just the right minty pow 💥
Teeth already looking better. Love the texture and the fact that you don’t have to spit it out if you don’t want to .

1 2 3

Reviews in Other Languages

Tastes great

Tastes great. Nice clean feeling. No idea if it actually does what it says but i feel better buying consciously.

I’m very happy with this toothpaste I have only been using it for a month however the difference in my teeth is amazing definitely ordering a second tube..
Taste is good too..

Tastes delicious!

1 2 3

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Gutology Hydroxyapatite Toothpaste 120ml